A 75-year-old woman with rheumatoid arthritis and multiple myeloma was admitted to the hospital with abdominal pain. She had ...

In four patients with severe autoimmune disease, teclistimab, a bispecific antibody to B-cell maturation antigen and CD3, ...

A woman with aggressive refractory systemic lupus erythematosus was treated with a short course of the bispecific antibody ...

In Western countries, the current standard of care for resectable gastric cancer is perioperative chemotherapy. Preoperative chemoradiotherapy has been considered, but data are limited regarding ...

Pragmatic and cluster RCTs offer opportunities for advancing research but present ethical challenges. Addressing these challenges requires multidisciplinary expertise and meaningful collaboration.

Type 2 diabetes is a common yet complex disorder in which the key hormone for nutrient storage, insulin, is both ineffective and insufficient in most affected patients, resulting in high ...

A total of 187 patients underwent randomization. Of these patients, 40% had non–small-cell lung cancer, 32% had pancreatic cancer, and 29% had colorectal cancer. At 12 weeks, patients in the ...

For permission requests, please contact NEJM Reprints at [email protected] Clinicians routinely provide harm-reduction measures and anticipatory guidance for a range of complex health issues (e.g ...

Adjuvant therapy with durvalumab, with or without tremelimumab, may have efficacy in patients with limited-stage small-cell lung cancer who do not have disease progression after standard ...

For permission requests, please contact NEJM Reprints at [email protected] Panel A shows dereplicated reads from wastewater virome sequencing assigned to H5N1 from all samples with a validated ...

The addition of pembrolizumab to trastuzumab and chemotherapy in patients with gastric cancer improved both progression-free and overall survival as compared with trastuzumab and chemotherapy alone.