When Christian McCaffrey went down, the 49ers could take solace in the fact that they had another versatile and dynamic weapon in Deebo Samuel. For the next two games, the 49ers will be without both as Samuel reported to work with a calf strain that coach Kyle Shanahan said would likely keep him out two weeks.

San Francisco 49ers star Christian McCaffrey could miss more than the minimum of four games required on injured reserve, according to multiple reports.